Identifikasi Keragaman Gen TGF-β2 dan Asosiasinya dengan Sifat Pertumbuhan pada Ayam Tolaki

M. Akramullah; C. Sumantri; N. Ulupi; M. A. Pagala

doi:10.29244/jipthp.8.1.22-29

M. Akramullah Departemen Ilmu Produksi dan Teknologi Peternakan, Fakultas Peternakan, Institut Pertanian Bogor
C. Sumantri Departemen Ilmu Produksi dan Teknologi Peternakan, Fakultas Peternakan, Institut Pertanian Bogor
N. Ulupi Departemen Ilmu Produksi dan Teknologi Peternakan, Fakultas Peternakan, Institut Pertanian Bogor
M. A. Pagala Fakultas Peternakan, Universitas Halu Oleo, Kendari

DOI: https://doi.org/10.29244/jipthp.8.1.22-29

Abstrak

The transforming growth factor-beta 2 (TGF-β2) gene is a group of growth hormone (GH) genes that control the nature of growth and belongs to the cytokine group. This study aimed to identify Single Nucleotide Polymorphism (SNP) g.640 T>C from the TGF-β2 gene then associated with the growth properties of tolaki chickens. Chicken blood samples used in this study amounted to 70 birds. Data on the nature of growth observed include; hatched weight, feed consumption, body weight, body weight gain and feed conversion. The TGF-β2 gene polymorphism was identified using the PCR-RFLP method. SNP g.640 T>C in the TGF-β2 gene was polymorphic and wasin Hardy-Weinberg balance. Identification results found 2 alleles, namely T and C and 3 genotype namely TT, TC, and CC. The association of TGF-β2 gene diversity in tolaki chicken generally showed a difference (P<0.05) on feed consumption, body weight and body weight gain. CC genotype has higher feed consumption, body weight, weight gain and more efficient feed conversion than TC and TT genotypes.

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