Pumpkin Soygurt Improves Blood Glucose Homeostasis in Diabetes Mellitus Rats Model

Annisa Avelia; Didik Gunawan Tamtomo; Yulia Sari

doi:10.25182/jgp.2023.18.Supp.1.93-95

Annisa Avelia, Didik Gunawan Tamtomo, Yulia Sari

https://doi.org/10.25182/jgp.2023.18.Supp.1.93-95

Issue
Vol. 18 No. Supp.1 (2023)

Published
30 December 2023

Keywords:

fasting blood glucose, HOMA-IR, insulin, QUICKI, synbiotic

PDF

Abstract

The study aimed to analyze the effect of pumpkin yogurt on insulin resistance in a rat model. The experiment employed 30 male Wistar rats divided into six groups: three control groups (healthy, negative, and positive) and three treatment groups (metformin+PS 1 mL, 1.5 mL, 2 mL). The experiments were conducted for four weeks. Blood glucose homeostasis was measured by fasting blood glucose, insulin, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), and Quantitative Insulin-Sensitivity Check Index (QUICKI). Administrating a combination of metformin and pumpkin soygurt can control blood glucose homeostasis with an effective dose of 1 mL. Further research should be done on the hormone incretin, which plays a role in insulin secretion.

References

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Authors

Annisa Avelia

Postgraduate Program of Clinical Nutrition, Universitas Sebelas Maret, Surakarta 57126, Indonesia AND Departement of Nutrition, Poltekkes Kemenkes Malang, Malang 65112, Indonesia

annisa.avelia@poltekkes-malang.ac.id (Primary Contact)

Didik Gunawan Tamtomo

Faculty of Medicine, Universitas Sebelas Maret, Surakarta 57126, Indonesia

Yulia Sari

Department of Parasitology, Faculty of Medicine, Universitas Sebelas Maret, Surakarta 57126, Indonesia

AveliaA., TamtomoD. G., & SariY. (2023). Pumpkin Soygurt Improves Blood Glucose Homeostasis in Diabetes Mellitus Rats Model . Jurnal Gizi Dan Pangan, 18(Supp.1), 93-95. https://doi.org/10.25182/jgp.2023.18.Supp.1.93-95