Toxicity Extract and Faction of Surian <i>Toona sinensis</i> Leaf and Bark  against Shrimp Larvae <i>Artemia salina</i> L.

Rori Theresia; Syamsul Falah; Mega Safithri; Muhammad Assyar

Rori Theresia Department of Biochemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University
Syamsul Falah Department of Biochemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University
Mega Safithri Department of Biochemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University
Muhammad Assyar Department of Biochemistry, Faculty of Mathematics and Natural Sciences, Bogor Agricultural University

Keywords: Artemia salina, BSLT, LC50, Surian, Toxicity

Abstract

Surian (Toona sinensis) is one of the herbs that contain many bioactive compounds. Part of surian plants that can be utilized as therapy is leaf and bark. This study aims to determine the toxicity of leaf and bark extract of Surian through Bhrine Shrimp Lethality Test (BSLT), then compare toxic concentration of water extract, and ethanol 70 %, and n-hexane, diethyl ether and ethyl acetate fractions to shrimp larvae (Artemia salina L). The results showed that water content of leaves simplicia was 8.08 % and bark was 6.26 %. The highest extract rendement value by ethanol solvent was 23 %. The result of BSLT test probit analysis showed that the extract of ethyl acetate bark fraction had the highest toxicity with LC50 value 405.641 ppm, while leaf water extract had the lowest toxicity with LC50 value 707.787 ppm.